Scientific Research

Scientific Research

Ubiquinol Scientific Research

Combining Ubiquinol With a Statin May Benefit Hypercholesterolaemic Patients With Chronic Heart Failure

Authors: Kloer H-U, Berlardinelli R, Ruchong O, Rosenfeldt F
Published: Heart, Lung and Circulation (2020) 29, 188–195 1443-9506/04
Link: https://www.heartlungcirc.org/article/S1443-9506(19)31444-1/fulltext

Myocardial energetics and ubiquinol in diastolic heart failure.

Authors: Bates A, Shen Q, Hiebert JB, Thimmesch A, Pierce JD.
Published: Nursing and Health Sciences, 16(4):428-33, 2014
Read study: www.ncbi.nlm.nih.gov/pubmed/25263245

Ubiquinol-induced gene expression signatures are translated into altered parameters of erythropoiesis and reduced low density lipoprotein cholesterol levels in humans.

Authors: Schmelzer C, Niklowitz P, Okun JG, Haas D, Menke T, Döring F.
Published: IUBMB Life, 63(1):42-8, 2011

Read study: www.ncbi.nlm.nih.gov/pubmed/21280176

Effect of carni Q-gel (ubiquinol and carnitine) on cytokines in patients with heart failure in the Tishcon study.

Authors: Kumar A, Singh RB, Saxena M, Niaz MA, Josh SR, Chattopadhyay P, Mechirova V, Pella D, Fedacko J.
Published: Acta Cardiologica, 62(4):349-54, 2007

Read study: www.ncbi.nlm.nih.gov/pubmed/17824295

The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.

Authors: Mortensen SA, Rosenfeldt F, Kumar A, Dolliner P, Filipiak KJ, Pella D, Alehagen U, Steurer G, Littarru GP, Q-SYMBIO Investigators.
Published: JACC: Heart Failure, 2(6):641-9, 2014

Read study: www.ncbi.nlm.nih.gov/pubmed/25282031

The effect of coenzyme Q10 in statin myopathy

Authors: Zlatohlavek L, Vrablik M, Grauova B, Motykova E, Ceska R.
Published: Neuro Endocrinology Letters, 33 Suppl 2:98-101, 2012

Read study: www.ncbi.nlm.nih.gov/pubmed/23183519

Supplemental ubiquinol in patients with advanced congestive heart failure.

Authors: Langsjoen PH, Langsjoen AM.
Published: Biofactors, 32(1-4):119-28, 2008

Read study: www.ncbi.nlm.nih.gov/pubmed/19096107

Short-term ubiquinol supplementation reduces oxidative stress associated with strenuous exercise in healthy adults: a randomized trial.

Authors: Sarmiento A, Diaz-Castro J, Pulido-Moran M, Moreno-Fernandez J, Kajarabille N, Chirosa I, Guisado IM, Javier Chirosa L, Guisado R, Ochoa J.
Published: Biofactors, 42(6):612-622, 2016

Read study: www.ncbi.nlm.nih.gov/pubmed/?term=27193497

Ubiquinol supplementation enhances peak power production in trained athletes: a double-blind, placebo controlled study.

Alf D, Schmidt ME, Siebrecht SC.
Published: Journal of the International Society of Sports Nutrition, 10:24, 2013

Read study: https://www.ncbi.nlm.nih.gov/pubmed/23627788

A randomized, double-blind trial on the bioavailability of two CoQ10 formulations

Authors: Evans M, Baisley J, Barss S, Guthrie N
Published: Journal of Functional Foods, 1(1):65-73, 2009

Read study: www.sciencedirect.com/science/article/pii/S175646460800011X

Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers.

Authors: Hosoe K, Kitano M, Kishida H, Kubo H, Fujii K, Kitahara M.
Published: Regulatory Toxicology and Pharmacology, 47(1):19-28, 2007

Read study: www.ncbi.nlm.nih.gov/pubmed/16919858

Ubiquinol Effect on Sperm Parameters in Subfertile Men Who Have Astheno-Teratozoospermia With Normal Sperm Concentration

Authors: Cakiroglu B, Eyyupoglu SE, Gozukucuk R, Uyanik BS.
Published: Nephro-urology Monthly, 6(3):e16870, 2014

Read study: www.ncbi.nlm.nih.gov/pubmed/25032137

Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study.

Authors: Safarinejad MR, Safarinejad S, Shafiei N, Safarinejad S.
Published: The Journal of Urology, 188(2):526-31, 2012

Read study: www.ncbi.nlm.nih.gov/pubmed/22704112

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References

Saini R. Coenzyme Q10: The essential nutrient. Journal of Pharmacy and Bioallied Sciences. 2011;3(3):466-467.
Evans M, Baisley J, Barss S, Guthrie N. A randomized, double-blind trial on the bioavailability of two CoQ10 formulations. Journal of Functional Foods, 2009; 1(1):65-73.
Langsjoen, P. H. and Langsjoen, A. M. (2014), Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone. Clinical Pharmacology in Drug Development, 3: 13–17.
Wada H et al (2007) Redox status of coenzyme Q10 is associated with chronological age. JAGS; 55: 1141-1142.
Bhagavan HN, Chopra RK. Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations. Mitchondrion 2007;S7:S78-88.
Skarlovnik A, Janic M, Lunder M, Turk M, Sabovic M. Coenzyme Q10 Supplementation Decreases Statin-Relted Mild-to-Moderate Muscle Symptoms: A Randomized Clinical Study. Med Sci Monit, 2014; 20:2183-2188.
Zlatohlavek, L, et al. The effect of coenzyme Q10 in statin myopathy. Neuroendocrinol Letters, 2012; 33: 98-101.
Rahman K. Studies on free radicals, antioxidants, and co-factors. Clinical Interventions in Ageing. 2007;2(2):219-236.
Ernster L, Dallner G. Biochemical, physiological and medical aspects of ubiquinone function. Biochim Biophys Acta. 1995;1271(1):195-204.
Alf D, Schmidt ME, Siebrecht SC. Ubiquinol supplementation enhances peak power production in trained athletes: a double-blind, placebo controlled study. Journal of the International Society of Sports Nutrition. 2013;10:24.

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No information included on this site should be construed as medical advice. Please consult your doctor or qualified health practitioner for medical advice. Never delay or disregard seeking medical advice because of something you have read on this website. Never substitute any of your medication for Ubiquinol.