Healthy Ageing

Ubiquinol Supports Healthy Ageing

Ubiquinol supports general health and wellbeing as we age. It helps maintain cellular energy production, energy levels, reduces cellular oxidative damage and supports cardiovascular, cognitive health and overall vitality. Highly absorbable, Ubiquinol is essential for supporting key bodily functions as we age.

Supports Mitochondrial Function

Ubiquinol is a critical component in mitochondrial energy production, helping to maintain cellular energy levels as we age.

Powerful Antioxidant Activity

As a potent lipid-soluble antioxidant, Ubiquinol helps reduce cellular damage from free radicals as we age. Increased production of free radicals may lead to oxidative stress, which is more prevalent as we age.7-9

Supports Cardiovascular Health

Ubiquinol helps maintain a healthy cardiovascular system and healthy cholesterol.9-18

Supports Cognitive Health

Ubiquinol helps maintain cognitive function.19-20

Highly Bioavailable

As we begin to age, we are exposed to higher levels of oxidative stress and the body’s endogenous production of Ubiquinol begins to wane which may lead to declining Ubiquinol levels.25-26
Kaneka Ubiquinol™ is highly absorbable and helps maintain levels in older adults.

Clinically Researched and Proven

Backed by over 100 clinical studies, Kaneka Ubiquinol™ is a scientifically validated supplement that supports healthy ageing

1. Pizzorno J. Mitochondria – Fundamental to life and health. Integra Med 2014;13(2):8-15.

2. Neupane P, et al. ATP synthase: Structure, function and inhibition. BioMol Concepts 2019;10:1-10.

3. Schirrmacher V. Mitochondria at work: New insights into regulation and dysregulation of cellular energy supply and metabolism. Biomedicines 2020;8(11).

4. Annesley SJ, Fisher PR. Mitochondria in health and disease. Cells 2019;8(7).

5. Hernandez-Camacho JD, et al. Coenzyme Q10 supplementation in aging and disease. Front Physiol 2018;9:44.

6. Rodick TC, et al. Potential role of coenzyme Q10 in health and disease conditions. Nutrition Dietary Supp 2018;10:1-11.

7. Molyneux SL, et al. Coenzyme Q10: Is there a clinical role and a case for measurement? Clin Biochem Rev 2008;29:71-82.

8. Varela-Lopez A, et al. Coenzyme Q and its role in the dietary therapy against aging. Molecules 2016;21(3):373.

9. Cirilli I, et al. Role of coenzyme Q10 in health and disease: an update on the last 10 years (2010-2020). Antioxidants (Basel) 2021;10(1325):1-24.

10. Di Lorenzo A, et al. Clinical evidence for Q10 coenzyme supplementation in heart failure: From energetics to functional improvement. J Clin Med 2020;9(5):1266.

11. Soni A, et al. Coenzyme Q10 therapy in current clinical practice. Intern J Res Med Sci 2015;3(4):817.

12. Rabanal-Ruiz Y, et al. The use of coenzyme Q10 in cardiovascular diseases. Antioxidants (Basel) 2021;10(5):755.

13. Gao L, et al. Effects of coenzyme Q10 on vascular endothelial function in humans: a meta-analysis of randomized controlled trials. Atherosclerosis 2012;221(2):311-316.

14. Kawashima C, et al. Ubiquinol improves endothelial function in patients with heart failure with reduced ejection fraction: A single-center, randomized double-blind placebo-controlled crossover pilot study. Am J Cardiovasc Drugs 2020;20(4):363-372.

15. Onur S, et al. Association between serum level of ubiquinol and NT-proBNP, a marker for chronic heart failure, in healthy elderly subjects. Biofactors 2015;41(1):35-43.

16. Sabbatinelli J, et al. Ubiquinol ameliorates endothelial dysfunction in subjects with mild-to-moderate dyslipidemia: a randomized clinical trial. Nutrients 2020;12(4):1098.

17. Zhao D, et al. Dose-response effect of coenzyme Q10 supplementation on blood pressure among patients with cardiometabolic disorders: A grading of recommendations assessment, development, and evaluation (GRADE)-assessed systematic review and meta-analysis of randomized controlled trials. Advances in Nutrition 2022;13(6):2180-2194.

18. Pierce JD, et al. Effects of Ubiquinol and/or D-ribose in patients with heart failure with preserved ejection fraction. Am J Cardiol 2022;176:79-88.

19. Kinoshita T, et al. The effects of ubiquinol (reduced form of coenzyme Q10) on memory, attentiveness, and work processing ability in healthy middled-aged and elderly residents – a randomized, double-blind, placebo-controlled trial. Jpn Pharmacol Ther 2021;49:1739-1747.

20. Fernández-Portero C, et al. Coenzyme Q10 levels associated with cognitive functioning and executive function in older adults. J Gerontol A Biol Sci Med Sci 2023;78(1):1-8.

21. Fischer A, et al. Coenzyme Q10 status as a determinant of muscular strength in two independent cohorts. PLoS One 2016;11(12):e0167124.

22. Moreno-Fernandez J, et al. Ubiquinol short-term supplementation prior to strenuous exercise improves physical performance and diminishes muscle damage. Antioxidants (Basel)2023;12(6):1193.

23. Diaz-Castro J, et al. Beneficial effect of ubiquinol on hematological and inflammatory signaling during exercise. Nutrients 2020;12(2):424.

24. Mizuno K, et al. Ubiquinol-10 intake is effective in relieving mild fatigue in healthy individuals. Nutrients 2020;12(1640):1-14.

25. Kalén A, Appelkvist EL, Dallner G. Age-related changes in the lipid compositions of rat and human tissues. Lipids. 1989;24(7):579-84.

26. Wada H, et al. Redox status of coenzyme Q10 is associated with chronological age. JAGS. 2007;55:1141-1142.

Ask your health practitioner or local pharmacist for the best product for you. Always read the label and use only as directed
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DISCLAIMER

No information included on this site should be construed as medical advice. Please consult your doctor or qualified health practitioner for medical advice. Never delay or disregard seeking medical advice because of something you have read on this website. Never substitute any of your medication for Ubiquinol. Always read the label and follow the directions for use. Always read the label and follow the directions for use.

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